Unstable iron (mainly in the form of ferrous iron) can react with oxygen and produce ROS, such as hydroxyl radicals and hydrogen peroxide, which are related to lipid peroxidation and tissue damage induced through the Fenton reaction
In 2020, the same team further reported that a higher dose (3200 mg/day) failed to improve depression beyond placebo effects, but side effects including abdominal discomfort (31%) and fluid retention (25%) became significantly more common 19
Conclusion The link between glutathione and weight loss is rooted in overall cellular health
10.1056/NEJMoa1401739 N Engl J Med
There are several ways to boost the bodys natural production of glutathione, including eating a diet rich in glutathione precursors like sulfur-containing foods, consuming antioxidant-rich foods, reducing exposure to toxins and pollutants, exercising regularly, and getting enough restful sleep